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Conditions

Headache red-flag triage

Structured headache approach emphasizing secondary-cause red flags and safe outpatient follow-up boundaries.

Last reviewed 2026-02-07|headache | neurology | triage

Assessment priorities

  • Characterize onset, severity, pattern change, and associated neurologic symptoms.
  • Review medication overuse, sleep, hydration, and blood pressure contributors.
  • Screen for infection, pregnancy, trauma, and vascular risk context.

Red flags

  • Thunderclap onset or worst headache of life.
  • Focal neurologic deficits, altered mental status, seizure, or papilledema concern.
  • Fever with meningeal signs, new severe headache in immunocompromised patients, or progressive neurologic decline.

Initial management

  • Classify likely primary headache only after red-flag screening is negative.
  • Use conservative symptomatic management and avoid low-value imaging where no red flags exist.
  • Provide clear explanation of uncertainty and planned reassessment interval.

Follow-up and escalation

  • Reassess if headache pattern evolves or fails to improve as expected.
  • Escalate urgently for new neurologic signs, severe refractory symptoms, or systemic instability.
  • Coordinate specialist referral when diagnostic uncertainty or complexity persists.